Metadoxil 500 mg Metadoxinum 10 tabs - Alcohol Intoxication Treatment & Withdrawal Syndrome.
METADOXIL 500 mg tablets
Metadoxine
Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.
Always take this medicine exactly as described in this leaflet or as your doctor or pharmacist has told you.
- Do not throw this leaflet away as you may need to read it again.
- If you want to know more or consult, contact your pharmacist.
- If side effects occur (even if they are not listed in this leaflet), contact your doctor or pharmacist. See Chapter 4.
If your condition has not improved or even worsened within 7 days, consult a doctor.
What is this leaflet about?
What METADOXIL is and what it is used for
What you need to know before taking METADOXIL
How to take METADOXIL
Possible side effects
How to store METADOXIL
Package contents and other information
What METADOXIL is and what it is used for
METADOXIL contains the active substance metadoxine, which is used in case of alcohol poisoning. This medicine lowers the amount of alcohol in the blood and helps to eliminate it in the urine.
METADOXIL tablets are used as an adjunctive medicine to relieve symptoms caused by chronic ethyl alcohol poisoning and to treat alcohol-induced liver disease.
If your condition has not improved or even worsened within 7 days, you must consult a doctor.
What you need to know before taking METADOXIL
METADOXIL should not be used:
- if you are allergic to methadoxin or any of the excipients of this medicine (they are listed in section 6);
- if you are breast-feeding a baby (see subsection "Pregnancy, breast-feeding and fertility").
Warnings and precautions
Talk to your doctor or pharmacist before taking METADOXIL
Use this medicine with caution and tell your doctor if you have Parkinson's disease and it is being treated with levodopa, as methadoxin may weaken the effect of this medicine (see the subsection "Other medicines and METADOXIL").
For children and teenagers
METADOXIL is not recommended for children and adolescents.
Other medicines and METADOXIL
Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, or if you are not sure.
Use this medicine with caution and tell your doctor if you have Parkinson's disease and are being treated with levodopa, as methadoxin may make this medicine less effective.
Pregnancy, lactation and fertility
If you are pregnant, breast-feeding, think you may be pregnant, or are planning to become pregnant, talk to your doctor or pharmacist before taking this medicine.
Pregnancy
During pregnancy, METADOXIL can only be used if absolutely necessary and only under the direct supervision of a doctor.
Breastfeeding period
Do not use METADOXIL if you are breast-feeding a baby, as methadoxin reduces the amount of a hormone called prolactin in the blood (causing a hypoprolactinemic effect) (see the subsection "Do not use METADOXIL").
Driving and machine control
METADOXIL does not affect the ability to drive and use machines.
How to take METADOXIL
Always take this medicine exactly as described in this leaflet or as your doctor or pharmacist has told you. If in doubt, ask your doctor or pharmacist.
For adults
For chronic alcohol poisoning and alcohol-induced liver disease, the recommended daily dose is two 500 mg tablets.
For elderly people
Elderly people can be treated with METADOXIL safely, there is no need to change the dose.
For patients with impaired liver function
For liver disease such as alcoholic liver disease, the recommended dose of METADOXIL can be used. Patients with severe liver dysfunction are advised not to take this medicine for a long time.
For patients with impaired renal function
There is no experience of treatment with METADOXIL in patients with impaired renal function. Given the fact that the drug is partially excreted from the body through the kidneys, these patients are advised to reduce the dose and not to take this drug for a long time.
Use in children and adolescents
METADOXIL is not recommended for use in children and adolescents, as safety and effectiveness have not been studied for them
Duration of treatment
If the condition has improved after 7 days of using METADOXIL, the treatment can be continued for 2-3 months if necessary. It can be continued up to 6 months after consultation with the doctor.
What to do if you overdose on METADOXIL?
Cases of overdose are unknown.
If you have taken too much METADOXIL at once, contact your doctor immediately or go to the nearest hospital.
If you forget to take METADOXIL
Do not take a double dose to make up for a missed dose
When you stop taking METADOXIL
METADOXIL works as long as it is used. Its effects disappear quickly when it is stopped.
If you have any further questions about the use of this medicine, ask your doctor or pharmacist.
Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
You may experience the side effects listed below.
Very rare (may affect up to 1 in 10,000 people):
allergic reactions (hypersensitivity);
numbness, tingling, tenderness and weakness in the hands and feet (peripheral neuropathy). These symptoms appear especially when the drug is used for a long time, after stopping the treatment, they tend to disappear;
dizziness and disorientation;
diarrhea, vomiting;
swelling of the face, lips, mouth, tongue or throat that may make swallowing and breathing difficult (angioedema), skin irritation (rash, hives), itching;
loss of appetite.
Differentiating side effects from symptoms caused by the underlying disease can be difficult in some cases.